Reactivation of precore mutant hepatitis B virus in chemotherapy-treated patients
نویسندگان
چکیده
منابع مشابه
Reactivation of hepatitis B virus in patients receiving chemotherapy.
In patients undergoing chemotherapy for the treatment of malignant disease, the reactivation of hepatitis B virus in hepatitis B surface antigen-positive patients has been frequently reported. However, activation has also been reported in hepatitis B surface antigen-negative patients who test positive for hepatitis B core antibody and/or hepatitis B surface antibody, who were thought to have ha...
متن کاملFulminant hepatitis subsequent to reactivation of precore mutant hepatitis B virus in a patient with lymphoma treated with chemotherapy and rituximab.
We report a case of a precore mutant hepatitis B virus (HBV) reactivation in a patient with follicular lymphoma who was treated simultaneously with chemotherapy (cyclophosphamide, vincristine and prednisone) and rituximab, occurred five months after the end of therapy. Despite lamivudine therapy, she died because of fulminant hepatitis. This case illustrates the possibility of late reactivation...
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Introduction: The hepatitis B virus (HBV) is one health problem in Iran. Occult hepatitis B (OBI) is diagnosed by the detection of HBV DNA in the serum or liver tissue of patients for whom other serology, especially HBsAg and HBcAg, are negative. The current study aimed to determine the prevalence of OBI in patients who refer for chemotherapy. Methods: Al...
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Hepatitis B virus (HBV) infection is common across the world. Infection can lead to significant morbidity from cirrhosis and hepatocellular carcinoma. An estimated 240 million people have chronic (hepatitis B surface antigen [HBsAg]-positive) HBV infection.[1] As a result of increasing immigration from highly endemic areas (eg, China, Southeast Asia, Africa, Eastern Europe), the prevalence of c...
متن کاملManagement of chemotherapy-induced hepatitis B virus reactivation.
Hepatitis B virus (HBV) reactivation induced by cytotoxic chemotherapy is an important issue in cancer patients. An elevated HBV viral load usually precedes hepatitis flare, and hepatic decompensation and eventual death is not infrequent once viral reactivation is initiated. Reverse seroconversion from hepatitis B surface antigen (HBsAg)-negative to HBsAg-positive would also occur in hepatitis ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2001
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(20011201)92:11<2927::aid-cncr10109>3.0.co;2-w